In the USA, The IVF industry is experiencing a pressing, double-edged problem: it struggles to fill new embryologist positions, an estimated 5% of the existing workforce is already beyond retirement age (65-67 years old)—and an estimated additional 20-40% will reach retirement age within the next 7 years. Embryologists are the core of the IVF supply chain, and a shocking “grey” rhino (an obvious yet ignored threat) is in the room. We cannot make more embryos without more embryologists. By all predictions, the IVF industry is on track to grow astoundingly in the next ten years as millennials who have put off childbearing for career begin to seek age-related infertility care. We are so focused on growing good embryos, but how do we grow (attract) new embryologists? 

An ASRM practice document [1]“Minimum standards for practices offering assisted reproductive technologies: a committee opinion” states that:

“There should be a contingency plan in place for all personnel essential to a program in case of illness, absence, or departure of an individual from the program. The purpose of the contingency plan is to ensure that critical operations within the laboratory and practice are covered without interruption.” 

Our entire field is in dire need of a contingency plan.

40% of our current workforce is attributed to the “Baby Boomer” generation. The oldest Baby Boomers are 75 years old, and the youngest are now 58. I would wager to guess that the vast majority of 67-75 year olds have already retired. Just think of the IVF lab directors and embryologists you know who will retire in the next 5-7 years (i.e. the 58-65 year olds). Each one likely directs numerous offsite laboratories. And new IVF laboratories open every day. Are enough new HCLD certificates being granted to ensure that IVF labs can continue to function at high levels of patient care and quality after this looming tsunami of retirements? 

As a result of this human capital conundrum, it has become even more important that IVF clinics ensure knowledge transfer, retention, and upskilling occur. 

Knowledge Transfer 

Campbell et al. note in “The in vitro fertilization laboratory: teamwork and teaming”[2] that “Knowledge sharing is vital among an IVF laboratory team to build on the knowledge base and enable succession and development. Clinical case review, journal-based learning, and research opportunities all facilitate such sharing and knowledge building.” Embryologists who are struggling to simply complete the expected clinical laboratory work of the day may not be able to fulfill these ideals, as well as train and supervise junior team members. 

The model of meeting for scientific congresses, where this type of knowledge transfer typically occurs, was briefly derailed during the global coronavirus pandemic. Scientific congresses can only serve a fraction of embryologists. The long overdue International IVF Initiative (I3) rose, modernizing the age-old practice of knowledge transfer with the added benefit of democratizing access for embryologists worldwide. Alternate approaches to further modernize the concept of “knowledge transfer” in embryology and the ARTs are so important. Chocair et al [3] proposed a robust roadmap to modernize knowledge transfer that includes multiple digital methods; online self-assessment programs, digital technology integration through blogs, podcasts, and influential videos, an online platform education management platform to report training logbooks, including a “knowledge assessment passport” among other action items. The Y and Z generations of workers are digital natives (digital “junkies” even..) they cannot live without their mobile devices. Investment in and support for “digital first” knowledge transfer technologies is essential. (Full disclosure, I am the inventor of one such unsupported technology, the ART Compass mobile app, so it goes without saying, these opinions are biased). 

Embryologist Retention

There is a childcare crisis in the USA. The majority of embryologists are women of childbearing years. These two things are essentially incompatible. 

Embryologist schedules are unpredictable (consider the odd 100 egg retrieval or 6 hour TESE) and can start well before a school day begins and stretch until well after a school day ends. Additional childcare considerations must be made for holidays and weekend shifts. That doesn’t even take into consideration the mental anguish of missing significant family related events or milestones. An added consideration is that families rarely reside in multi-generational households (or even in the same city) and Baby Boomers are no longer retiring in a timely fashion due to a combination of economic fragility brought on by multiple successive economic failures and longer life-spans. Even when they do retire, they don’t necessarily want to watch little ones. They have already raised their own children and are ready for travel, adventure, and leisure. Many embryologists are confronted with a very simple calculus: “Do I make enough in one hour to cover one hour of childcare?” With the skyrocketing cost of childcare as well as the scarcity of available childcare providers, too often that answer is “no”. 

One action item for the field at large is to train more male embryologists. Diversifying the workforce will have numerous benefits; including, greater insulation from multiple maternity leaves of absence. However, an even more pressing need is to fix the culture of IVF practices to be less rigid, less demanding, and more flexible for those with families or even without, recognizing that work life balance will drive the decisions of Gen Z and Gen Y. And to do that, we must support the elevation of our female embryologists to the highest ranks (PhD/HCLD). It stands to reason that if 80% of embryologists are female, 80% of lab directors should also be female. However, we see the opposite is true. It is clear that when men do become embryologists, they quickly ascend the ranks to become lab directors, or presumptuously, I think they must leave the field because they won’t stand for the intense hours/ low pay/ holidays and weekends. So modulating the intense, unpredictable “culture” of IVF labs should have the impact of retaining both genders equally. 

Upskilling 

In the USA, we have few formal “embryologist” education, training, or placement programs. The bulk of all new embryologist training falls to the senior embryologists. This dearth, coupled with high embryologist demand has led to the rise of a number of commercialized and privatized training programs to fill the void. Currently, these programs have stellar reputations. But what is to stop predatory programs from also springing up? Generally, consumers of education programs have some level of assurance and transparency because there is oversite and regulation of higher education. Results are measurable and formally assessed and documented, sources of capital and cash flow are understood, the quality of training and/or placement is guaranteed. One action item for the field could be a standardized and digital education management platform to report training logbooks, that includes the “knowledge assessment passport” mentioned above. One example, and in response to the COVID-19 pandemic, the American Center for Reproductive Medicine (ACRM) transitioned its annual training to a fully online modules included manual semen analysis, sperm morphology and ancillary semen tests (testing for leukocytospermia, sperm vitality, and anti-sperm antibody screening)[4]. 

Conclusion

Within higher education, abundant models exist for hands on biotech training at the “associate degree” open enrollment level, but grow scarcer at the BS / BA level. Advocacy associations for the ART industry might focus lobbying efforts at State legislature levels that acknowledge that without an appropriately skilled workforce, it is impossible to grow this highly-regulated industry. Local ART education programs should eliminate barriers to ART careers by providing access to expensive equipment, space, and real-life education through hands-on learning opportunities, learning FDA, CLIA and other regulatory requirements that result in highly employable, and valuable technical careers in ART. An intriguing new study, Clinical Laboratory Workforce: Understanding the Challenges to Meeting Current and Future Needs [5] suggests further innovative ways to improve workforce recruitment and retention, including; financial incentives to encourage professional development and job satisfaction; and flexible schedules, benefits, tuition incentives, and sign-on bonuses. 

Acknowledgment 

Unpublished Online survey by the educational platform International IVF Initiative.

Palmer GA, Tully B, Angle M, Sadruddin S, Howles C, Nagy ZP, et al. Occupational Demand & Resultant Stress of reproductive scientists: Outcomes from an International survey.

References

  1. Practice Committee of the American Society for Reproductive Medicine, P.C.o.t.S.f.A.R.T., B. Practice Committee of the Society of Reproductive, and a.a.o. Technologists. Electronic address, Minimum standards for practices offering assisted reproductive technologies: a committee opinion. Fertil Steril, 2021. 115(3): p. 578-582.
  2. Campbell, A., et al., The in vitro fertilization laboratory: teamwork and teaming. Fertil Steril, 2022. 117(1): p. 27-32.
  3. Choucair, F., N. Younis, and A. Hourani, The value of the modern embryologist to a successful IVF system: revisiting an age-old question. Middle East Fertility Society Journal, 2021. 26(1): p. 15.
  4. Agarwal, A., et al., A Web-Based Global Educational Model for Training in Semen Analysis during the COVID-19 Pandemic. World J Mens Health, 2021. 39(4): p. 804-817.
  5. Edna C. Garcia, M., M. Iman Kundu, and P. and Melissa A. Kelly, Clinical Laboratory Workforce: Understanding the Challenges to Meeting Current and Future Needs. . 2021.

 

Preventing errors in the IVF Lab is the top priority of every embryologist. But how do they happen, and what can we do about them? 

Have you ever driven home, but didn’t know how you got there? That’s your brain on autopilot mode. Brain scans have revealed that when your mind wanders, it switches into this mode to enable you to carry on doing tasks quickly and reasonably accurately, but without conscious thought. 

“Autopilot mode” one of the most dangerous times for an embryologist. Reasonable accuracy is not acceptable in what we do. Yet, as human beings, we all make errors. Sometimes, your brain and eyes just don’t see what’s right there in front of you. 

Part of embryologist training is not just learning the technical procedures, but training your brain to not take “shortcuts.” We do this by implementing a set of tricks to constantly kick the grey matter from autopilot mode back into full consciousness on a regular basis. Each embryologist must develop their own magic set of tricks to ensure nearly 100% accuracy, always. The eyes of a junior embryologist must be trained to actually SEE what is in front of them, and to not accept what our brain wants us to see, or what one THINK they should be seeing (i.e. seeing an empty dish when there are really embryos in it!). Even “seniors” can be lulled I into complacency by many years without an error, until and unexpected are truly horrific mistake happens out of the blue. 

The unique nature of IVF and fertility care demands an incredibly high standard to avoid errors. This makes embryology a medical professions with one of the highest rates of stress and burnout. You can never just “put it on autopilot” or lose concentration, even for a second. The consequences can be catastrophic for both patients and the clinic. 

While mistakes may occasionally be due to system failures, malfunctioning equipment, or a break in the chain of custody, the hardest type to deal with, especially in the lab, is simple human error. 

Here are 4 tips to prevent human error in the IVF lab. 

In fertility care, any instance in which gametes or embryos are lost, degraded, or misdirected constitutes an adverse event – a medical error. The comprehensive training and accreditation of an embryologist is designed to minimize any potential impact on patient samples.

Fortunately, IVF errors are rare. A study published recently found that in a 10-year period (2009 to 2019), 133 errors occurred that resulted in lawsuits out of approximately 2.5 million IVF procedures in the U.S. A 2018 study of non-conformance with standards from the International Organization for Standardization found that 99.96% of procedures (36,654 IVF treatment cycles) in one clinic network had zero violations.

I’ve had both my best day and my worst day as an embryologist. While research on the unconscious mind has shown that the brain makes judgments and decisions quickly and automatically, I look forward to an AI-enabled lab, where repetitive and mundane tasks are automated and intelligent, AI-enabled tools monitor and control safety with precision and ease. 

Do you have story to share when an error occurred in the lab and you were able to correct it? 

Spring is a season of new life, renewal, and growth. It’s a time when the earth awakens from its winter sleep and bursts forth with vibrant colors and new beginnings. For those struggling with infertility, spring can symbolize hope and the possibility of new life.

If you’re waiting to get pregnant, the journey can be long and difficult. It’s easy to become overwhelmed with the daily routine of charting cycles, taking medications, and undergoing fertility treatments. But as the days get longer and warmer, it’s important to take a step back and appreciate the beauty of the season and the hope it brings.

Just as the earth goes through cycles of growth and renewal, so do our bodies. Infertility can be a frustrating and emotional rollercoaster, but it’s important to remember that every cycle is a new beginning. With each new cycle, there’s the possibility of new life, and the hope that this time will be the one.

Oocytes, or eggs, undergo a complex process of maturation before they can be fertilized. This process takes several months, and is influenced by a variety of factors, including age, genetics, and lifestyle choices. There are steps that individuals can take to support the maturation process and increase their chances of conception. One of the most effective ways is to make lifestyle changes and incorporate certain supplements into the daily routine.

For example, studies have shown that maintaining a healthy weight, exercising regularly, and reducing stress levels can all positively impact oocyte maturation and improve fertility. In addition, taking supplements such as folic acid, vitamin D, and omega-3 fatty acids can also support the maturation process and improve overall reproductive health.

Spring is also a time for self-care and renewal. Take some time to pamper yourself, whether it’s with a relaxing bubble bath, a massage, or a day out in nature. Focus on activities that bring you joy and relaxation, and don’t forget to connect with loved ones for support.

The season of renewal also provides an opportunity to reflect on your fertility journey and set new goals. Take some time to reassess your priorities, and consider any lifestyle changes that might improve your chances of conceiving. This could mean adjusting your diet, exercise routine, getting enough high quality sleep, or reducing stress levels.

Remember, you’re not alone on this journey. Seek out support from friends, family, or a professional counselor if you’re feeling overwhelmed. Spring is a season of new beginnings, and with each new cycle, there’s the possibility of new life and hope.

So, as you embrace the season of spring, remember that your journey towards parenthood is also a journey of growth and renewal. Take a deep breath, appreciate the beauty around you, and have faith that your new beginning is just around the corner